Abstract

The esterolytic enzymes of fresh extracts of liver, pancreas and serum of dogs have been studied, using α-naphthyl butyrate, caprylate and laurate as substrates. Eserine salicylate, sodium taurocholate, potassium fluoride, sodium arsanilate, di-isopropylfluorophosphate (D.F.P.), diethyl- p-nitrophenylphosphate, E600, and quinine hydrochloride were employed as inhibitors or accelerators. In the liver, the presence of an esterase proper and some pseudocholinesterase has been demonstrated. In the serum, a considerable amount of pseudocholinesterase and a pancreatic type of lipase were found. The presence in the pancreas of an esterase proper is discussed.

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