Abstract
Rationale. Malnutrition might be present in people living with HIV/aids (PHIV/aids), and be associated with derangement of the immune system. Objective. To assess the association between the nutricional status of the PHIV/aids and the counts of T CD4+ cells. Study design. Observational, analytical and cross-sectional. Methods. The nutricional status of 217 PHIV/aids in the Pinar del Rio province, Cuba (Men: 72.4%; Age at the moment of HIV/aids diagnosis: 0.05); Chang’s algorithm: ORContingencyTable = 2.55 (p = 0.047); and SGA: ORContingencyTable = 1.72 (p > 0.05); respectively. When the study serie was adjusted according anti-retroviral therapy (ARVT), association between CD4+ and nutritional status was as follows: BMI: ORLogisticRegression = 0.367 (p = 0.083); Chang’s Algorithm: ORLogisticRegression = 2.604 (p = 0.050); and SGA: ORLogisticRegression = 1.714 (p = 0.232); respectively. Conclusions. Inception of ARVT modifies the association that might exist between the immune system and nutritional status. Reduction of CD4+ counts in a PHIV/aids was weakly associated with derangement of nutritional indicators. It is likely that body weight excess might be modifying this association: 29.0% of the studied PHIV/aids had BMI values >= 25.0 Kg.m-2.
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