Abstract
Three groups of rats were placed on sucrose morphine and milled rat food for 25 days. Morphine HCl content was.5 mg/ml for all three groups. Sucrose concentrations were 2.5%, 5%, and 10%. In a subsequent choice test, all three groups selected their respective sucrose morphine over tap water. In an additional choice test given to the 10% group, the rats selected the sucrose morphine over the vehicle. We report on a highly effective oral method of inducing morphine preference.
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