Establishment of a Linear Correlation Model of Central Venous Blood Oxygen Saturation and Lactate in Sepsis

Abstract

Introduction: Studies have shown that there is a complex relationship between lactate and ScvO2. Methods: A retrospective study was carried out in 37 intensive care patients with sepsis or septic shock. The relationship between lactate and ScvO2 was explored with correlation analysis and simple linear modelling. Results: Lactate and ScvO2 were significantly correlated in patients with septic shock (r2 = 0.46, p = 0.001; y = -4.11x+ 82.62), but not in sepsis. y Significant correlation between these parameters was also found in the group of patients who went on to die (r2 = 0.67, p < 0.01; y = -3.70x + 78.61), but not in patients who survived. Conclusions: In sepsis, the correlation between ScvO2 and lactate is not constant over the sepsis course and may be dynamic. In the resuscitation of sepsis and/or septic shock, changes in ScvO2 requires further study.