Establishment of a human induced pluripotent stem cell line (CSUASOi010-A) by reprogramming peripheral blood mononuclear cells of a type 2 diabetic mellitus patient

Chengcheng Ding,Feng Tan,Yalan Zhou,Chunwen Duan,Jianing Gu,Zekai Cui,Zhongping Chen,Shibo Tang,Jiansu Chen

doi:10.1016/j.scr.2022.102851

Establishment of a human induced pluripotent stem cell line (CSUASOi010-A) by reprogramming peripheral blood mononuclear cells of a type 2 diabetic mellitus patient

Chengcheng Ding, Feng Tan + Show 7 more

Open Access

https://doi.org/10.1016/j.scr.2022.102851

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Journal: Stem Cell Research	Publication Date: Jul 7, 2022
License type: cc-by-nc-nd

Affiliation: He Eye Hospital, Central South University, Jining Medical University, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Jinan University

#Induced Pluripotent Stem Cell Line #Human Induced Pluripotent Stem Cell + Show 8 more

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Abstract

Type 2 diabetes mellitus (T2DM) is a major caused by insulin resistance with a relative deficiency in insulin secretion. Statistically, T2DM accounts for 90% of diabetes cases worldwide. We report the patient-specific human induced pluripotent stem cell line (iPSC) CSUASOi010-A by using Peripheral blood mononuclear cells (PBMCs) of a 62-year-old female from Type 2 diabetes mellitus (T2DM). Patient blood-derived cells were reprogrammed using the Sendai virus.

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