Abstract

Objectives. In this prospective study, we intend to establish the psychometric properties of ICOAP for its use in studies involving the Hellenic population. Methods. SF-36 Health Survey was used as a standard against ICOAP scores from a sample of 89 patients (mean age: 71.07, 69 females) with hip and knee OA pain who underwent 2 treatment cycles of 4 intra-articular injections of sodium hyaluronate, separated by a 12-week medication-free time interval. Both questionnaires were filled twice with no missing data during follow-up. Results. ROC analysis accomplished ICOAP's criterion-related validation. Wilcoxon Signed-Rank Test and paired samples t-test endorsed ICOAP's responsiveness along with Effect Size values, standard response mean, and Relative Efficiency. Comparisons between the areas under curves (AUC) on ROC plots established external responsiveness. Cronbach's-alpha value favored ICOAP's internal consistency. This, along with intraclass correlation, results in both advocated reliability and content validity. Interitem discrimination was demonstrated by the ease of completion of ICOAP as well as the degree of familiarity with it. These findings inaugurated construct validity in collaboration with Spearman's and One-Way ANOVA results. Conclusions. ICOAP is a valid, reliable, and responsive QoL instrument and suitable for studies of osteoarthritic joint pain in the Greek setting.

Highlights

  • During recent decades, the ongoing increase in life expectancy has shifted the interest of health professionals towards new ways of disease management

  • Among developed healthrelated quality of life (HRQoL) questionnaires focused on osteoarthritic pain, the Intermittent and Constant Osteoarthritis Pain (ICOAP) questionnaire for hip and knee osteoarthritis, a relatively new assessment tool, is the first to introduce the distinction of OA hip and knee pain in its two components: constant (ICOAP-constant pain (CP)) and intermittent (ICOAP-intermittent pain (IP)) pain

  • Eligible participants were individuals diagnosed with single joint OA-related pain lasting for 3 months or more and meeting the clinical and radiographic criteria established by the American College of Rheumatology [3], along with Kellgren and Lawrence radiographic OA classification [4]

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Summary

Introduction

The ongoing increase in life expectancy has shifted the interest of health professionals towards new ways of disease management. Keeping in mind a variety of conservative and surgical treatment methods that are still in use, it becomes obvious that osteoarthritic pain comes into play as a major healthrelated quality of life (HRQoL) determinant that challenges any country’s health system efficiency in terms of burden of disease. Among developed HRQoL questionnaires focused on osteoarthritic pain, the Intermittent and Constant Osteoarthritis Pain (ICOAP) questionnaire for hip and knee osteoarthritis, a relatively new assessment tool, is the first to introduce the distinction of OA hip and knee pain in its two components: constant (ICOAP-CP) and intermittent (ICOAP-IP) pain. This distinction provides detailed information for each of these two kinds of pain separately as well as for total pain, forming a global view which differs from “pain on activity” as measured by all the preexisted questionnaires [1].

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