Abstract

научный биометрический журнал, который знакомит читателя с клиническими рекомендациями и особенностями применения лекарственных и вакцинных средств у детей, предоставляет исчерпывающую информацию о воздействии лекарственных средств на плод, о проводимых в

Highlights

  • Pyelonephritis is one of the most widespread urinary system diseases in children [1, 2]

  • Microelement homeostasis study results indicated that a statistically significant reduction in the level of essential microelements Se, Cu and Zn in blood serum of children was observed in the active stage and in the period of decline in activity of pyelonephritis in comparison with the control group (p

  • We revealed a statistically significant reduction in excretion of selenium and copper with urine, while the level of Zn excretion did not differ from the control group values

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Summary

Introduction

Pyelonephritis is one of the most widespread urinary system diseases in children [1, 2]. Increase in the number of scarcely manifested and latent disease course forms complicates timely diagnostics and, postpones beginning of adequate therapeutic, rehabilitative and preventive measures. This pathology is disposed to chronization, recurrence and progression with formation of nephrosclerosis and development of renal failure, which result in incapacitation of patients [3, 4]. Such severe consequences make further detailed study of etiology and pathogenesis of the disease relevant. The aim of the study is to analyze microelement homeostasis (Zn, Cu, Se, Pb, Cd) in biological media (blood serum, daily urine) in children with recurrent pyelonephritis depending on activity of the pathological process

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