Abstract

This will allow the reader to appreciate the evolution of knowledge and concepts in the area of the original article, based on work that has been achieved since it was first published, in line with progress in medical science and technology. Obviously, the longer the time from the original publication, the greater the changes that are to be seen. It may become evident that, with the advances in technology, the interpretation of the physiological/pathophysiological phenomena related to a particular disease indeed differs from that of the original paper.

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