Abstract
The immunologist Emil von Behring was awarded the first Nobel Prize in Physiology or Medicine in 1901. The citation read: “For his work on serum therapy, especially its application against diphtheria, by which he has opened a new road in the domain of medical science and thereby placed in the hands of the physician a victorious weapon against illness and deaths.” Passive antibody therapy thus had an auspicious beginning. Paul Ehrlich's side-chain theory of antibody formation achieved widespread popularity and was a precursor of F Macfarlane Burnet's clonal selection hypothesis.
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