Abstract

A woman, aged thirty-seven, was examined at the clinic August 3, 1925. Twenty-eight years previously a swelling had appeared over the right tibia, without ulceration; this persisted for several months but finally disappeared following the local application of iodin. Soon afterward the cervical glands became greatly enlarged, and there was bilateral corneal ulceration. One and one-half years later a swelling appeared over the left tibia, just below the knee; this ulcerated and drained for seven vears. When the patient was fourteen, the larynx was ulcerated, and there was aphonia for a year, followed by permanent impairment of phonation. Three years later, she had indefinite upper abdominal distress accompanied by vomiting of large amounts of blood, and she was confined to bed for eighteen weeks. She had difficulty in swallowing, and strangled and coughed on ingesting liquids, which was attributed to the previous laryngeal ulceration. When she was nineteen years of age pain developed in the left side of the...

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