Abstract
Esophageal Varices: Pathophysiology, Approach, and Clinical Dilemmas
Highlights
The dominant cause of portal hypertension relates to liver cirrhosis which increases resistance through the hepatic sinusoids
Gastroesophageal varices are the most important clinical manifestation of this syndrome and are associated with a high risk of upper gastrointestinal hemorrhage and its attendant high mortality. This special issue includes nine evidence-based reviews. They discuss the pathophysiology of portal hypertension as well as its clinical manifestations and management
Yokosuka review the current concepts of the pathophysiology of portal hypertension and esophageal varices
Summary
Editorial Esophageal Varices: Pathophysiology, Approach, and Clinical Dilemmas Portal hypertension is one of the most significant complications of both acute and chronic liver diseases. The dominant cause of portal hypertension relates to liver cirrhosis which increases resistance through the hepatic sinusoids. Gastroesophageal varices are the most important clinical manifestation of this syndrome and are associated with a high risk of upper gastrointestinal hemorrhage and its attendant high mortality.
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