Esophageal squamous papilloma associated with adenocarcinoma

Abstract

Squamous papilloma of the esophagus, first reported by Adler et al. 1 Adler RH Carberry DM Ross CA Papilloma of the esophagus. Association with hiatus hernia. J Thorac Surg. 1959; 37 (1959;37:625-35): 625-635 PubMed Google Scholar in 1959, is a well-described entity with a prevalence of 14 per 100,000. 2 Harrer WV Sprague TH Keeley FX Squamous cell papilloma of the esophagus. A case report and literature review. J Med Soc NJ. 1975; 72: 229-232 PubMed Google Scholar The literature indicates that this lesion is benign. Although squamous papilloma has been associated with squamous cell carcinoma of the larynx 3 Toso G Epithelial papillomas—benign or malignant? Interesting findings in laryngeal papilloma. Laryngoscope. 1971; 81: 1524-1531 Crossref PubMed Scopus (42) Google Scholar and cervix, 4 Qizilbash AH Papillary squamous tumors of the uterine cervix. Am J Clin Pathol. 1974; 61: 508-520 PubMed Google Scholar , 5 Kistner RW Hertig AT Papillomas of the uterine cervix—their malignant potentiality. Obstet Gynecol. 1955; 6: 147-161 PubMed Google Scholar it has not been associated with carcinoma of the esophagus. In this report, we describe the first case of a squamous papilloma associated with an adenocarcinoma at the gastroesophageal junction. We think this case report has important implications in the surveillance and management of esophageal polyps found at endoscopy.