Abstract
In this article, we reported a clinical case of late posttransplant complication – esophageal actinomycosis in 58-yr-old woman 8 months after heart transplantation. Recipient had presented with a complaint of dyspeptic phenomena. Patient’s examination did not show any features. Blood results were fine but tacrolimus concentration was increased (24 ng/ml). Esophagogastroduodenoscopy identified signs of esophageal candidiasis, biopsy was taken. Histological examination revealed esophageal actinomycosis. According to other investigations we did not find any signs of antinomycosis in other organs. Taking into account the results of obtained research, there was no evidence of deep tissue invasion and no indications for surgical treatment, conservative management was chosen. Three months of antibacterial treatment (Doxycycline) was effective. Considering long-term management of this complication in out-patient department it is important to accomplish strictly the protocol of posttransplant follow-up, the same as it allows to diagnose in time. Conservative management of esophageal actinomycosis diagnosed on early stage can be effective.
Highlights
In this article, we reported a clinical case of late posttransplant complication – esophageal actinomycosis in 58-yr-old woman 8 months after heart transplantation
В биохимическом анализе крови обращало на себя внимание повышение уровня креатинина до 124 мкмоль/л, С-реактивный белок был
Olofinlade and Bruce Javors – Esophageal Actinomycosis: A Case Report and Review of the Literature
Summary
We reported a clinical case of late posttransplant complication – esophageal actinomycosis in 58-yr-old woman 8 months after heart transplantation. Известно всего о 20 случаях актиномикоза пищевода [2]. Развитие актиномикоза пищевода ассоциировано со снижением иммунитета, вызванного применением иммуносупрессивной терапии, лучевой терапии или у ВИЧ-инфицированных пациентов [2,6,7]. T. Yagi et al опубликовали данные об актиномикозе пищевода у 19-летнего пациента через 9 месяцев после проведенной трансплантации костного мозга по поводу лимфомы [4]. R.D. Welling et al опубликовали клинический случай о выявлении актиномикоза пищевода у пациента после трансплантации почки [5].
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