Esclerosis tuberosa. Hallazgos clínicos en 67 pacientes

Abstract

BackgroundTuberous sclerosis is an uncommon neurocutaneous syndrome characterized by the appearance of hamartomas in multiple organs. Diagnosis is based on clinical criteria. ObjectiveTo report the clinical findings in a series of 67 patients with tuberous sclerosis. Material and methodsThis was a descriptive and observational retrospective study of patients with tuberous sclerosis referred to our dermatology clinics between January 1994 and March 2007. ResultsAll patients presented neurological or dermatological disorders. Other disorders, in descending frequency, were psychiatric (55.5 %), renal (32.8 %), cardiac (22.4 %), skeletal and pulmonary (13.4 %), and ophthalmological (11.9 %). ConclusionsWe report the clinical findings in a series of patients with tuberous sclerosis. According to our literature search, this is the first such study in the Spanish population. Overall, our findings support those already published.