Abstract
ESC/EAS Guidelines for the management of dyslipidaemias
Highlights
The Task Force for the Management of Dyslipidaemias of the European Society of Cardiology (ESC) and European Atherosclerosis Society (EAS)
Total risk estimation using a risk estimation system such as Systemic Coronary Risk Estimation (SCORE) is recommended for asymptomatic adults >40 years of age without evidence of Cardiovascular disease (CVD), diabetes, chronic kidney disease (CKD) or familial hypercholesterolaemia
Throughout this section it should be noted that most risk estimation systems and virtually all drug trials are based on total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C), and that clinical benefit from using other measures, including apolipoprotein B (apoB), non-HDL-C and various ratios, while sometimes logical, has largely been based on post hoc analyses
Summary
Cardiovascular disease (CVD) kills .4 million people in Europe each year. It kills more women [2.2 million (55%)] than men [1.8 million (45%)], cardiovascular (CV) deaths before the age of 65 years are more common in men (490 000 vs. 193 000).[1]. Cardiovascular disease (CVD) kills .4 million people in Europe each year It kills more women [2.2 million (55%)] than men [1.8 million (45%)], cardiovascular (CV) deaths before the age of 65 years are more common in men (490 000 vs 193 000).[1] Prevention is defined as a coordinated set of actions, at the population level or targeted at an individual, aimed at eradicating, eliminating or minimizing the impact of CV diseases and their related disability. Individual level, in those at moderate to high risk of CVD or patients with established CVD, by tackling an unhealthy lifestyle (e.g. poorquality diet, physical inactivity, smoking) and by reducing increased levels of CV risk factors such as increased lipid or blood pressure levels. Prevention is effective in reducing the impact of CVD; the elimination of health risk behaviours would make it possible to prevent at least 80% of CVD and even 40% of cancers, providing added value for other chronic diseases.[3,4]
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