Abstract

Liver abscess of hydatid origin as a risk factor for postoperative complications in hydatidosis Background: Cyst infection and subsequent abscess formation is considered a complication of hepatic echinococcosis (HE). Aim: To determine whether liver abscess of hydatid origin (LAHO) is a risk factor for the development of postoperative complications (POC) in patients operated by HE. Material and Methods: Prospective cohort study. Patients consecutively operated by HE between 2000 and 2007 were studied. LAHO was considered as exposure and POC as outcome. Results: Fifty two patients with LAHO, aged 50 ± 21 years (52% females) and 126 without LAHO, aged 48 ± 20 years (56% females) were studied. Patients with LAHO had a higher frequency of coexistent cyst lesions and a lower frequency of biliary communications. The frequency of complications was 28.9 and 11.1% among patients with and without LAHO, respectively (p < 0.01, crude risk ratio of 2.6, 95% confidence intervals 1.4-5.0). Logistic regression showed a significant interaction of alkaline phosphatases with risk calculation. The risk ratio, adjusting by this variable, changed to 2.45 (95% confidence intervals 1.3-5.0). Conclusions: LAHO is a risk factor for the development of POC in patients operated by HE.

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