Abstract

Erythropoietin Response in Patients with Anaemia of Chronic Disorders

Highlights

  • Anemia of Chronic Disease (ACD) is one of the most common anemias worldwide, second only to Iron Deficiency Anemia (IDA)

  • The patients were enrolled from all outpatient clinics and all Medical and Surgical Wards at the Jos University Teaching Hospital. 5mls of blood were collected from all participants in the morning to determine full blood count, serum iron, serum ferritin levels, and serum EPO levels

  • For this study a total of 215 participants were recruited, 90 of which were controls (i.e patients seen at the outpatient clinics for routine/annual physical examination) and the remaining 125 subjects had some form of chronic disease

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Summary

Introduction

Anemia of Chronic Disease (ACD) is one of the most common anemias worldwide, second only to Iron Deficiency Anemia (IDA). It is the most frequent anemia among hospitalized patients with an average incidence of 6% between the ages of 18 to 60; and an incidence of 44.4% in men of 85 years and above. In healthy individuals and patients with haematological disorders, a drop in haematocrit, (e.g after haemorrhage) leads to a rise in serum EPO levels.

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