Abstract

SummaryOf 17 unconcentrated urine samples taken from 7 anemic humans, approximately 25% displayed erythropoietic stimulating properties. Blood volume and bone marrow studies confirmed the erythropoietic nature of the responses obtained. Urine from 4 children with normal hemoglobin levels showed no ability to stimulate erythropoiesis. When compared to anemic human plasma, anemic human urine is a more dilute and less constant source of erythropoietically active material.

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