Abstract
A patient is presented who exhibited a Henoch-Schönlein type of response after each of four administrations of quinine. At various times during these four episodes a number of typically immuno-hematologic disorders appeared: erythrophagocytosis, a serum factor that could induce erythrophagocytosis in normal blood, increased capillary fragility, transient diminution in numbers of platelets, abnormal platelet morphology, possible phagocytosis of platelets and decreased clot retraction. It is suggested that the occurrence of such immunohematologic phenomena, well known in other contexts to be due to specific antibody behavior, lends support to the contention that the Henoch-Schönlein syndrome is an example of antibody depredation upon tissues. The occurrence of erythrophagocytosis, induced by the activity of the patient's serum on normal blood, is especially strong associational evidence for this point of view.
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