Abstract

The aim of the present study was to obtain erythrocyte membrane fractions from patients with chronic active hepatitis caused by hepatitis B virus (HBV) and hepatitis C virus (HCV) infections. Na +,K + ATPase activities were significantly lower ( P<0.005) in HBV related chronic active hepatitis ( n=20, 0.134±0.073 μmol P/mg protein per h) and in HCV hepatitis ( n=11, 0.144±0.049 μmol P/mg protein per h) when compared to control group ( n=10, 0.219±0.055 μmol P/mg protein per h). Both types of chronic active hepatitis B and C have markedly altered erythrocyte membrane Na +,K + ATPase activities that can be indicative of hepatic cell damage in humans. Although HBV and HCV infections are based on diverse mechanisms of action on their effect in liver injury, they cause similar effects on membrane ATPase activities.

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.