Erythema Multiforme Caused by Treponema pallidum in a Young Patient with Human Immunodeficiency Virus Infection

Abstract

Erythema multiforme (EM) is usually caused by drug reactions or virus infection. We report a case of secondary syphilis presenting as EM in an HIV-infected patient, proved by immunohistochemical staining, which is rare in the literature. It is valuable to determine the etiology of EM to optimize treatment.