Abstract
Erythema Dyschromicum Perstans (EDP) / Ashy Dermatosis are a less common dermatological disorder with an unknown etiology. It is characterized by asymptomatic, grey, symmetric and confluent macules all over the body. Herein, we report a case of a 50 years old man who presented clinically, with diffuse, patchy pigmentation having ill-defined, erythematous borders involving bilateral arms and forearms. Histopathological examination of the lesion biopsy demonstrates vacuolar degeneration of the basal cell layer, dermal perivascular mononuclear cell infiltrate and increased epidermal melanin pigment and presence of dermal melanophages. For the present case, treatment with Clofazimine has proven to be effective.
Highlights
Erythema Dyschromicum Perstans (EDP) is a pigmentary disorder on the spectrum of acquired macular pigmentation. It is known as Ashy Dermatosis due to its clinical presentation
The patient was diagnosed with EDP from both clinical and histopathological findings
Clofazimine along with topical Mometasone has been used with some success, apparently because of their anti-inflammatory and immune-modulating effects
Summary
Erythema Dyschromicum Perstans (EDP) is a pigmentary disorder on the spectrum of acquired macular pigmentation. It is known as Ashy Dermatosis due to its clinical presentation. It is found in patients with skin phototypes III-IV [1].
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