Abstract

A 44-year-old man with hypertension and type 2 diabetes presented to the emergency department with unrelenting, substemal chest pain of 6 hours' duration. Physical examination findings were within normal limits except forhis lower extremities, which contained a myriad of 2- to 5-mm, red-yellow, dome-shaped papules with an erythematous halo coalescing into small plaques without exudates crust, or scales (figure 1). The patient reported that the skin lesions had first appeared 4 months earlier and had steadily increased in number. The lesions were occasionally pruritic. Electrocardiography revealed ST-segment elevation in the lateral leads, and cardiac enzyme levels were significantly elevated. The patient's random triglyceride level was above 3,500 mg/dL (39.52 mmol/L). Emergent three-vessel coronary bypass surgery was performed. The patient was instructed to adhere to a low-fat diet and begin statin therapy. Weeks after his hospitalization, the patient was free of chest pain, the skin lesions had diminished, and his fasting lipid profile was much improved.

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