Eruptive Sebaceous Hyperplasia A rare adverse effect of systemic corticosteroid use in two immunosuppressed patients

Abstract

Sebaceous hyperplasia is a benign, not uncommon cutaneous disorder. The disorder is caused by overabundance and proliferation of sebocytes in the sebaceous glands [1]. The proliferation induces enlargement of the sebaceous gland up to several times its regular size, but still keeping the normal anatomical structures. Sebacceous glands have a central duct that may become dilated in sebaceous hyperplasia due to secretion of an oily substance, sebum, which presents flesh- or yellowish coloured [2]. Sebaceous glands are localized everywhere on the skin except for palms and soles of the feet. The highest concentration of the glands is found on the face, the back, and the upper arms, which is also the most common places to encounter sebaceous hyperplasia [3]. Papules that are newly formed often swell during sweating which is pathognomonic for the disorder. Sebaceous glands are commonly associated with hair follicles, though may rarely present in hairless regions of the skin [4].