Abstract
Samples with analyte concentrations outside a method's dynamic range are a reality of clinical chemistry and are particularly of interest in method comparison studies. The most obvious remedy—to ignore any such values—introduces bias and loses the information that censored data might add to the analysis. Extending conventional errors‐in‐variables methods to incorporate value‐censored data recovers this information. The formulation presented uses a variance model more flexible than either the constant variance or the constant coefficient of variation models. Copyright © 2016 John Wiley & Sons, Ltd.
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