Abstract

Weber, K. (2017). Differences in Types and Incidence of Neoplasms in Wistar Han and Sprague-Dawley Rats. J Toxicol Pathol45, 64-75. (Original DOI: 10.1177/0192623316672075) In the January 2017 issue of Toxicologic Pathology, a number of in text Table citations were incorrectly labeled. The following are the sentences with corrected Table number (this has also been corrected in the online version): Many fewer neoplasms are recorded for the endocrine pancreas compared with islet cell tumor incidences (Table 3). The data presented in Table 4 are consistent with the high incidences mentioned for keratoacanthomas by various authors for SD (M. Chandra, Riley, and Johnson 1992; Nakazawa et al. 2001) and Wistar (Poteracki and Walsh 1998) rats. Mammary gland neoplasms are considered a major cause of morbidity/death (Weber et al. 2011; Table 6). The most common tumor in male F344 rats is the interstitial (Leydig) cell tumor at a mean incidence of 81% (Mitsumori and Elwell 1998; NTP 2010) but is also reported to reach almost 100% (Nolte et al. 2010; Table 6). Incidences at >0.5% are only reported for granulosa cell tumors or theca granulosa cell tumors, and the highest incidences are noted in Wistar strains (Table 7). Stromal sarcoma and leiomyoma were noted also at incidences >0.5% (Table 9). In Table 9, adenomas of the pars intermedia and anterior are combined due to the fact that several pathologists did not differentiate between these tumor types.

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