Abstract

HistopathologyVolume 60, Issue 7 p. 1169-1174 Free Access Erratum This article corrects the following: Pitfalls in the evaluation of melanocytic lesions Thomas Brenn, Volume 60Issue 5Histopathology pages: 690-705 First Published online: December 16, 2011 First published: 23 May 2012 https://doi.org/10.1111/j.1365-2559.2012.04319.xAboutSectionsPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat In Brenn,1 figures 3 to 10 were printed in black and white but should have been printed in colour. The colour figures are printed here. The publishers apologize for this error. (3) [ A,B, Mitotically active naevus. Mitotic activity is scarce and seen typically in the superficial aspect of the lesion. Also note the lack of melanocyte atypia (A). Low-power examination emphasizes the classical features of a banal naevus, including lesional circumscription, symmetry and maturation with depth (B). C,D, Naevoid melanoma. Despite the naevic low-power impression, the lesion appears cellular and shows a nodular growth pattern (C). Higher magnification shows the monotonous growth pattern of epithelioid melanocytes as well as mitotic activity in the deeper aspects (D). ] (4) [ Desmoplastic/sclerosing naevus. This low-power impression highlights the increased stromal fibrosis as well as lesional circumscription and symmetry (A). Individual melanocytes are epithelioid with somewhat spitzoid cytological features containing abundant cytoplasm and vesicular nuclei with small eosinophilic nucleoli. They are dispersed singly or in small aggregates within a desmoplastic stroma (B). Cellularity is increased in the superficial aspects (C). Melan A immunohistochemistry highlights lesional demarcation as well as architectural maturation with depth (D). ] (5) [ A,B, Deep penetrating naevus. The tumour appears somewhat wedge-shaped, with a plexiform growth pattern. Extension into superficial subcutis is characteristic (A). Melanocytes are arranged in short fascicles within dermis. They are ovoid, with abundant cytoplasm containing melanin pigment and vesicular nuclei with small nucleoli. There is a background of pigment laden histiocytes (B). C,D, Clonal naevus. An area of increased pigmentation is present in the deeper reaches of an otherwise banal dermal naevus (C). It is composed of nests of ovoid melanocytes cytologically reminiscent of those seen in deep penetrating naevus and pigment laden histiocytes (D). ] (6) [ Pigment synthesizing melanoma. This heavily pigmented tumour is based within dermis and extends multifocally into superficial subcutis (A). It is composed of heavily pigmented epithelioid to ovoid melanocytes with vesicular nuclei and prominent eosinophilic nucleoli (B). ] (7) [ Tumoral melanosis. Melanin-laden histiocytes form a nodular aggregate within dermis (A,B). ] (8) [ Cellular blue naevus. This large and heavily pigmented, dermal-based tumour extends into subcutis in a classical dumbbell shape (A,B). Melanocytes are ovoid and uniform, arranged in cellular nests of varying sizes. There is a background of pigmented dendritic cells and melanophages. Mitotic activity may be identified even in the deeper reaches (C). In areas, a sclerotic dermal response is seen and the appearances are reminiscent of more classical blue naevus (D). The alveolar pattern is characterized by pigmented dendritic cells surrounding the cellular nests of ovoid non-pigmented melanocytes (E). The amelanotic variant lacks discernible melanin pigment (F,G). ] (9) [ Plaque-type blue naevus. This rare variant of blue naevus shows a diffuse growth pattern within dermis and subcutis involving deeper underlying structures including galea (A,B). It is composed of uniform ovoid to spindled melanocytes in a background of pigmented dendritic cells. Despite the diffuse growth pattern, cytological atypia is not a feature (C). ] (10) [ Cutaneous clear cell sarcoma. This dermal-based tumour is composed of nests of spindle cells arranged in short fascicles separated by bands of collagen (A). There is cytological atypia and mitotic activity is easily identified (B). ] Reference 1 Brenn T. Pitfalls in the evaluation of melanocytic lesions. Histopathology 2012; 60; 690– 705. Wiley Online LibraryCASPubMedWeb of Science®Google Scholar Volume60, Issue7June 2012Pages 1169-1174 ReferencesRelatedInformation

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