Erratum

Abstract

Journal of NeurochemistryVolume 103, Issue 1 p. 423-424 Free Access Erratum This article corrects the following: Deposition of iron and β-amyloid plaques is associated with cortical cellular damage in rabbits fed with long-term cholesterol-enriched diets Othman Ghribi, Mikhail Y. Golovko, Brian Larsen, Matthew Schrag, Eric J. Murphy, Volume 99Issue 2Journal of Neurochemistry pages: 438-449 First Published online: July 28, 2006 First published: 28 August 2007 https://doi.org/10.1111/j.1471-4159.2007.04922.xAboutSectionsPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat In [1], 1, 4 were originally printed in error. The following figures and legends below are the corrected versions: Figure 1Open in figure viewerPowerPoint Cholesterol-enriched diets induced the accumulation of Aβ plaques and iron. (a) Representative photomicrograph showing the brain region (i) we examined in our studies, which consists of the hippocampus formation (ii) and the adjacent cortex (iii), which refers to the cerebral cortex that overlies the hippocampus and includes the somatomotor area through the lateral part of the entorhinal area. While Avidin-Biotin Complex staining with BC05 antibody reveals no immunoreactivity to BC05 in either the CA1 region of the hippocampus (b) or the adjacent cortex (c) in control rabbit, Aβ 42 plaques are present in the CA1 (d) of the cholesterol-treated rabbit. In the adjacent cortex the Aβ plaques are surrounded by iron (blue) as revealed by Prussian's blue staining (e). Bar, 50 μm. Figure 4Open in figure viewerPowerPoint Cholesterol treatment altered levels of apoptosis-regulatory proteins and caused DNA oxidation. (a) Representative Western blots of Bcl-2 and Bax in hippocampus (h) and adjacent cortex (c) from control (Ctl) and cholesterol-treated (Chl) rabbits. Cholesterol induces a decrease in Bcl-2 levels and an increase in Bax in the adjacent cortex. (b) Densitometric analysis showing that the treatment with cholesterol induces a significant decrease in Bcl-2 levels and a marked increase in the level of Bax in the adjacent cortex. *p < 0.05 (Two-way unpaired Student t-test). (c) Photomicrographs of sections from the CA1 area of the hippocampus and adjacent cortex in control (i and ii) and in cholesterol-treated (iii and iv) rabbits immunostained for 8- oxoguanine, a marker for DNA damage. While no immunoreactivity to 8-oxoguanine antibody is observed in tissue from a control rabbit, increased nuclear staining is observed in adjacent cortex (iv, arrowheads), but not in hippocampus (iii) of cholesterol-treated animals. Bar, 20 μm. Reference [1] Ghribi O., Golovko M. Y., Larsen B., Schrag M. and Murphy E. J. (2006) Deposition of iron and β-amyloid plaques is associated with cortical cellular damage in rabbits fed with long-term cholesterol-enriched diets. J. Neurochem. 99, 438– 449. Wiley Online LibraryCASPubMedWeb of Science®Google Scholar Volume103, Issue1October 2007Pages 423-424 FiguresReferencesRelatedInformation