Abstract

Acknowledgments Funding was provided by a National Science Foundation Predoctoral Fellowship (Grant No. 1000136529 to L.C.), the Welch Foundation (I-1770 to D.M.R, I-1544 to M.K.R., I-1424 to K.H.G.), the Searle Scholars Program (D.M.R), a Packard Foundation Fellowship (D.M.R), the National Institutes of Health (T32 GM008297 supporting J.Z., R01 GM106239 to K.H.G., R01GM56322 to M.K.R.) and the Howard Hughes Medical Institute (M.K.R.). NMR spectroscopy at UTSW is supported by NIH instrumentation grants 1S10RR26461-1 and 1S10OD018027-01.

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