Abstract

[This corrects the article DOI: 10.1155/2017/7928981.].

Highlights

  • In the last decade there has been a significant increase in complex lifestyle diseases like depression, diabetes mellitus (DM), cardiovascular diseases (CVD), cancer, and infertility

  • The findings suggest that the impact is mediated through improvement in genomic stability, telomere metabolism, and balance of cellular oxidative stress, well-regulated stress and inflammatory responses, and increase in neuroplasticity and nutrition sensing

  • Genomic stability is central to cellular longevity and disease-free youthful healthy life and the findings from our study suggest the reduction of genomic instability by yoga- and meditation-based lifestyle intervention (YMLI)

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Summary

Introduction

In the last decade there has been a significant increase in complex lifestyle diseases like depression, diabetes mellitus (DM), cardiovascular diseases (CVD), cancer, and infertility. These diseases are strongly associated with accelerated cellular aging [1, 2] and have become the bane of modern society [3–5]. The cardinal biomarkers of cellular aging include DNA damage, telomere length attrition, and oxidative stress (OS) [7]. Telomere attrition is due to altered telomere metabolism involving a decrease in telomerase enzyme activity and an increase in OS. It contributes to genomic instability and is associated with aging and lifestyle diseases [12]

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