Abstract

Background Previous work showed that the functional cardiac effect of dietary alpha-linolenic acid (ALA) in rats requires a long feeding period (6 months), although a docosahexaenoic (DHA) acid-supply affects cardiac adrenergic response after 2 months. However, the total cardiac membrane n-3 polyunsaturated fatty acid (PUFA) composition remained unchanged after 2 months. This delay could be due to a specific reorganization of the different subcellular membrane PUFA profiles. This study was designed to investigate the evolution between 2 and 6 months of diet duration of the fatty acid profile in sarcolemmal (SL), mitochondrial (MI), nuclear (NU) and sarcoplasmic reticulum (SR) membrane fractions.

Highlights

  • A mistake has been noted in our recently published (25 March 2009) article [1]. This error appeared in the material and methods section, and concerns the content of Table 1

  • An overlapping of the lines has occurred in the fatty acid profile section of the Table, due to an unfortunate insertion of the 22:2 n-6, a fatty acid that has nothing to do there

  • Total SFA Total MUFA Total PUFA Total n-6 PUFA Total n-3 PUFA

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Summary

Introduction

An overlapping of the lines has occurred in the fatty acid profile section of the Table, due to an unfortunate insertion of the 22:2 n-6, a fatty acid that has nothing to do there. Address: 1Institut National de la Recherche Agronomique (INRA)-Université Paris-Sud 11, Unité Mixte de Recherche 1154, Lipides Membranaires et Régulation Fonctionnelle du Coeur et des Vaisseaux, Institut Fédératif de Recherche 141, Faculté de Pharmacie, Châtenay-Malabry, F-92296, France and 2Société Valorex, Combourtillé, France

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