Erratum to: Drosophila AD3 mutation of synaptotagmin impairs calcium-dependent self-oligomerization activity (FEBS 24173) : [ FEBS Letters 482 (2000) 269–272

Abstract

The legend for ¢gure 4 was omitted. It should have read: `Diagram describing Ca2‡-independent and -dependent Syt II (or I) self-oligomerization of wild-type and AD3 (Y312N) mutant proteins. Schematic representations of Ca2‡-independent and -dependent oligomerization of wild-type (A), heterozygous (B), and homozygous AD3 mutant (C) Syt proteins. Transmembrane domain (TM) and C2 domains are represented by open boxes and hatched boxes, respectively. The shaded region around the transmembrane domain indicates Ca2‡-independent self-oligomerization, which was observed in every case (A^C). In A, wild-type proteins show e¤cient Ca2‡-dependent oligomerization (large double arrow) that is inhibited by IP4 [38,51]. In B, AD3 mutant proteins interact with wild-type proteins in a Ca2‡-dependent manner (small double arrow), whereas in C, AD3 mutant proteins fail to interact with each other in the presence of Ca2‡.'