Abstract

Interaction of 2-chloro-N-(9,10-dioxo-9,10-dihydroanthracen-1-yl)acetamide with α-, β- and ω-amino acids was used to synthesize new amino-acid derivatives of 9,10-anthraquinone. Experimental testing of the antimicrobial actions of the compounds synthesized demonstrated antibacterial activity against Mycobacterium luteum and antifungal activity against Aspergillus niger and Candida tenuis. These results from experimental testing of biological activity are consistent with results obtained by predictions using the computer program PASS. The prediction identified the need for further study of the antitumor and antioxidant actions of the newly synthesized amino acid derivatives.

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