Erratum: Synthesis of Some Aminophosphonates BearingN-(Fluorophenyl)-piperazynyl Moiety and Their Activity toward Serotonin Receptors

Abstract

Syntheses of a series of compounds bearing a 1-(fluorophenyl)piperazin-4-ylmethyl moiety, namely dialkyl 1-(fluorophenyl)piperazin-4-ylmethyl phosphonates 3a–f, diethyl 2-[1-(fluorophenyl)piperazin-4-yl]-ethyl phosphonates 4a,b, diethyl 3-[1-(4-fluorophenyl)-piperazin-4-yl]-propyl phosphonate 5, and di[1-(fluorophenyl)piperazin-4-yl]methanes 6a,b were performed, and some of them were screened for their affinity for serotonin 5-HT1A, 5-HT6, and 5-HT7 receptors. Moderate interactions with these receptors were demonstrated.