Abstract

Fig. 4 a ASR to a single pulse expressed as digital units (mean±SEM) at different acoustic background noises in 6-OHDA-lesioned Sprague– Dawley rats. Responses are compared with intact Sprague–Dawley rats. Two-way ANOVA did not indicate a significant effect of 6-OHDA lesioning F(1, 100)=2.157, p=0.1575, but significant effect of noise F(5, 100)=27.3 and interaction lesion×noise F(5, 100)=2.546, p=0.0326. Significant differences in Bonferroni-corrected post hoc t tests indicated by a single asterisk p<0.05. b PPI of the startle response expressed as percent (mean±SEM) of startle response. Two-wayANOVA indicated a main effect of background noise level, F(5, 100)=75.34, p<0.0001, but not of lesion treatment F(1, 100)=0.7398, p=0.3999 or interaction lesion×noise F(5, 100)=2.035, p=0.0801 The online version of the original article can be found at http://dx.doi. org/10.1007/s00213-010-2074-6.

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