Abstract

At the end of 2011, microbiologists created a scientific and media frenzy by genetically engineering mutant avian flu viruses that transmitted through the air between ferrets, the animal most widely used to model human flu. Though the studies offered new evidence of avian flu’s pandemic potential, they were nevertheless restricted from publication because of concerns about their possible threat to human health and security. In this article, I examine the mutant flu controversy to show how nascent biosecurity regulations engender transformations in experimental systems; namely, in the use and interpretation of experimental organisms, and in the establishment of a culture of security among a globalizing community of scientists. Drawing on analyses of academic publications, interviews with microbiologists and biosecurity regulators, and ethnographic observations at a biosecure laboratory, I show how these experimental transformations are structured by the local demands of scientific production as well as by broader concerns about biosecurity made visible in formal and informal regulations on scientific conduct. I further argue that while the controversy signals unprecedented controls over publication in the biological sciences, such controls build upon and extend on-going shifts in scientific thought and practice in the wake of pandemic threats.

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