Abstract

OPINION article Front. Microbiol., 16 November 2012Sec. Antimicrobials, Resistance and Chemotherapy Volume 3 - 2012 | https://doi.org/10.3389/fmicb.2012.00384

Highlights

  • Aarts on behalf of the authors of the original publication) would like to present here the correct nomenclature and mechanistic features of the antibiotic resistance genes belonging to the following classes: Aminoglycosides (Table 1), Phenicols (Table 3), Macrolides–Lincosamides– Streptogramin B (Table 4), Quinolones (Table 5), Tetracyclines (Table 6), and Trimethoprim (Table 7)

  • In addition some additional information is given on the various classes of antibiotic resistance genes as a section regarding the antibiotic class Oxazolidinones has been added

  • ACT: Acetyltransferase; MET: Methyltransferase; NUT: Nucleotidyltransferase; PHT: Phosphotransferase. aAlthough the sat genes are not aminoglycoside resistance determinants, they encode streptothricin-acetyltransferases, for convenience they are included in this table

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Summary

Accession number or reference

X15852 aac(3)-Ib aac(3)-Ibaac(6 )-Ib aac(3)-Ic aac(3)-Id aac(3)-Ie aac(3)-If aac(3)-Ig aac(3)-Ih aac(3)-Ii aac(3)-Ij aac(3)-Ik aac(3)-IIa. M88012 M22999 M55426 M55427 AB028210 AY553333 AJ628983 DQ302723 EU912537 M18967 M21682 EF636461 aac(6 )-Ic aac(6 )-Id aac(6 )-Ie; see aac(6 )-aph(2 )

Coding region
Number of variants*
Inactivating enzyme
Accession number
Mechanism Gene
Coding region Genera
Proteus Klebsiella
Accession Coding region number
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