Abstract
Erythema nodosum is the most frequent clinicopathologic variant of panniculitis. Triggers are represented by infections, sarcoidosis, rheumatologic diseases, inflammatory bowel disease, medications, autoimmune disorders, pregnancy and malignancy. Erythema nodosum typically manifests by the sudden onset of symmetrical, erythematous, warm nodules, usually located on the lower limbs. Often the lesions are bilaterally distributed. Treatment of erythema nodosum should be directed to the underlying associated condition, if identified. Usually, nodules of erythema nodosum regress spontaneously within a few weeks, and bed rest is often sufficient treatment. Nonsteroidal antiinflammatory drugs and potassium iodide may be helpful drugs to enhance analgesia and resolution. Systemic corticosteroids are rarely indicated in erythema nodosum and before these drugs are administered, an underlying infection should be ruled out.
Highlights
Erythema nodosum is the most frequent clinicopathologic variant of panniculitis
Corticosteroizii sistemici sunt rar indicaţi în eritem nodos
8. Moraes A.J., Soares P.M., Zapata A.L., Lotito A.P., Sallum A.M., Silva C.A. Panniculitis in childhood and adolescence
Summary
Vasile Valeriu Lupu, Ancuţa Ignat, Gabriela Stoleriu, Angelica Cristina Marin, Gabriela Păduraru, Marin Burlea. Eritemul nodos este cea mai frecventă variantă clinicopatologică de paniculită. Factorii declanşatori sunt reprezentaţi de infecţii, sarcoidoză, boli reumatologice, boli inflamatorii intestinale, medicamente, tulburări autoimune, sarcină şi tumori maligne. Eritemul nodos apare de obicei brusc şi se manifestă prin noduli simetrici, eritematoşi, calzi, cel mai frecvent localizaţi pe membrele inferioare. Tratamentul eritemului nodos ar trebui să fie îndreptat către agentul cauzal, dacă acesta este identificat. Nodulii eritemului nodos pot regresa spontan în câteva săptămâni şi repausul la pat este adesea suficient. Antiinflamatoarele nonsteroidiene şi iodura de potasiu pot ajuta la analgezie şi rezoluţie. Corticosteroizii sistemici sunt rar indicaţi în eritem nodos. Trebuie exclusă infecţia ca şi factor declanşator al eritemului
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