Abstract
Objective The aim of this study was to determine the role of psoriasis per se in erectile dysfunction (ED). Background An association between psoriasis and ED has been explored and proved in several studies. However, not much is known about the role of psoriasis per se in the pathogenesis of ED in these patients. Patients and methods This case–control study included 40 male participants aged 25–50 years who were divided into two groups: a case group composed of 20 psoriatic patients with moderate to severe psoriasis and an age-matched control group composed of 20 healthy men. All participants completed the International Index of Erectile Function version-5 questionnaire and the hospital anxiety and depression scale (HADS). Results The results of the study showed that there was no significant difference in ED percentage in the psoriasis group compared with the control group (25 vs 5%, P = 0.076) and there were significant differences in anxiety and depression indices in the psoriasis group compared with the control group (HADS score for anxiety 55% normal, 15% borderline, and 30% abnormal vs 85% normal, 15% borderline, P = 0.026 while the HADS score for depression was 50% normal, 25% borderline, and 25% abnormal vs 80% normal, 20% borderline, P = 0.039). Conclusion Psoriasis per se has no role in ED.
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