Abstract
Erectile dysfunction (ED) affects a growing number of men in the United States and abroad, with significant impacts on sexual function and overall quality of life. The etiologies of ED are classified as organic or psychogenic, with the majority of causes being organic. The most common organic cause of ED is vasculogenic, although other major classes of ED etiologies include neurologic, endocrine, drug-induced, iatrogenic, and other medical and urological disorders. Clinicians are well served to keep in mind that virtually all cases of apparently organic ED have a psychogenic component. The risk factors for ED include cardiovascular disease and its associated risk factors, and men with ED should be routinely screened for cardiovascular disease. Additional risk factors for developing ED include diabetes, lower urinary tract symptoms, hypogonadism, and other chronic conditions. Having a clear understanding of the etiologies and risk factors for ED facilitates the workup of ED and the development of a personalized, effective treatment approach.
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