Abstract

Industrial anthropogenic activities pollute water and contaminate fish with heavy metals. The study presented a chemically modified carbon paste sensor for Cu (II) ion assay based on Cu-erdosteine association complex. The electrode exhibited a Nernstian response (29.6 ± 0.018 mV/decade) with a wide linear concentration range (1.99 ×10−6 −1 ×10−2 mol L−1). Over the pH range of 4.0–6.0, the potentiometric response of the fabricated electrode is independent of pH. The sensor determined the Cu (II) content in drug substances, pharmaceutical formulations, and tuna meat via potentiometric titration with EDTA. The method did not differ statistically from the method described in the literature.

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