Abstract
Erasmus syndrome is a rare pathology defined as a systemic sclerosis secondary to contact with silica, associated or not with silicosis. More recent studies have related silica as an environmental factor stimulating different immune responses of the body. This report was made with the objective of presenting a rare case of systemic sclerosis, in a localized cutaneous form, also called CREST syndrome. A patient with a 20-year history of mining developed silicosis, cutaneous calcinosis, Raynauld's phenomenon, esophagopathy, sclerodactyly, telangiectasias and high positivity for the antitopoisomerase I antibody, the most common antibody in the systemic form.
Highlights
Erasmus syndrome is a rare pathology defined as a systemic sclerosis secondary to contact with silica, associated or not with silicosis
Erasmus syndrome is defined by the development of systemic sclerosis (SSc) secondary to silica, with or without the presence of silicosis [1]
91 Erasmus syndrome presented as CREST syndrome with Scl-70 positivity: a case report relative risk (ERRC) in relation to silica was 3.20 for men undergoing meta-analysis [4]
Summary
Erasmus syndrome is defined by the development of systemic sclerosis (SSc) secondary to silica, with or without the presence of silicosis [1]. Erasmus syndrome is a rare pathology defined as a systemic sclerosis secondary to contact with silica, associated or not with silicosis. This report was made with the objective of presenting a rare case of systemic sclerosis, in a localized cutaneous form, called CREST syndrome.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
