Abstract

Peste des Petits Ruminants (PPR) is a highly contagious viral disease of both domestic (goats and sheep) and wild ruminants. Caused by a morbillivirus, that belongs to the family Paramyxoviridae. The disease is clinically and pathologically similar to rinderpest of cattle and human measles. PPR is one of the most economically devastating viral diseases of small ruminants. In April 2015, the Food and Agriculture Organization of the United Nations (FAO) and the World Organisation for Animal Health (OIE) launched the PPR Global Control and Eradication Strategy (PPR GCES) with the vision for global eradication by 2030. There is a strong and lasting international consensus to eradicate the disease in order to protect the livelihoods of the world’s poorest populations. As with any disease, eradication is feasible when, policy, scientific and technical challenges are addressed. Ten majors challenges are described in this paper namely: understanding small ruminant production, facilitating research to support eradication, refining laboratory testing, improving epidemiological understanding of the virus, defining infection of wildlife and other species, optimizing vaccine delivery and novel vaccines, developing better control of animal movement, heightening serological monitoring, understanding socio-economic impact, and garnering funding and political will.

Highlights

  • Among the 198 countries recognized by the United Nations, 57 have already have Peste des Petits Ruminants (PPR)-free status as per May 2019 according to Organisation for Animal Health (OIE) Standards, while 67 are infected and 74 have never reported PPR

  • PPR Global Control and Eradication Strategy (GCES) was subsequently turned into the PPR Global Eradication Programme (PPR GEP)

  • It is currently unclear whether these infections are relevant from an epidemiological and eradication perspective; it is essential to fully understand the role of wildlife in the spread and potential maintenance of PPRV in the environment in order to be able to initiate successful control strategies

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Summary

The Disease and Its Impacts

Peste des Petits Ruminants (PPR) is a highly contagious and devastative viral disease of both domestic (goats and sheep) and wild small ruminants. Success a related morbillivirus of cattle, rinderpest virus (RPV) eradication

TheResources
International Coordination of the PPR-GCES
The Global Vaccination Strategy for PPR Eradication
Key Challenges to the Eradication Campaign Programme?
Research to Facilitate Eradication
Role of Laboratory Testing in the Eradication Campaign
Improving Epidemiological Understanding of PPRV
Infection of Wildlife and Other Species
Vaccine Delivery and Novel Vaccines
Applying Movement Controls and Providing Better Channels for Communication
Accurately Assessing Socio-Economic Impact
3.10. Funding and Political Will
Findings
Conclusions
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