Abstract
Equine herpesvirus 1 isolates from a 2021 outbreak of neurologic disease in Europe have a mutation, A713G, in open reading frame 11 not detected in 249 other sequences from equine herpesvirus 1 isolates. This single-nucleotide polymorphism could help identify horses infected with the virus strain linked to this outbreak.
Highlights
Equine herpesvirus 1 isolates from a 2021 outbreak of neurologic disease in Europe have a mutation, A713G, in open reading frame 11 not detected in 249 other sequences from equine herpesvirus 1 isolates
Equine herpesvirus 1 (EHV-1) is a threat to the equine industry, as demonstrated by the ongoing outbreak of neurologic disease initially reported at a large equestrian event in Valencia, Spain
We tested 19 positive samples by the allelic-discrimination real-time PCR for a single-nucleotide polymorphism (SNP), A2254G, within open reading frame (ORF) 30, which has been associated with the neuropathogenic phenotype of EHV-1 (1)
Summary
4. Rudakov NV, Shpynov SN, Yastrebov VK, Samoylenko IE, Kumpan LV, Reshetnikova TA, et al The present state of the problem of rickettsioses in Russia and new approaches to the classification of diseases caused by spotted fever group Rickettsiae [in Russian]. Equine herpesvirus 1 isolates from a 2021 outbreak of neurologic disease in Europe have a mutation, A713G, in open reading frame 11 not detected in 249 other sequences from equine herpesvirus 1 isolates.
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