Abstract
Experiments on the equilibrium sedimentation in CsCl density gradients of the DNA from adult mouse tissues, three tumors, mouse tissue culture cells, and from three different tissues of the monkey, the guinea-pig, and the alligator are described. The DNA banding patterns were characteristic for each species. Bimodal distributions were observed for mouse and guinea-pig DNA. The mean buoyant densities of the principal and the satellite mouse DNA bands were 1·701 and 1·690 g cm −3 , respectively. The mean buoyant density of the major guinea-pig DNA band was 1·697 g cm −3 , and that of the minor band was 1·703 g cm −3 . A single band was found in the case of monkey or alligator DNA but these differed in mean buoyant density and in band variance. The mean buoyant densities and the band variance were the same for the differentiated tissues of a given animal species.
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