EPS7.07 Impact of newborn screening for cystic fibrosis – preliminary results from Norway

Abstract

Objective: In Norway, newborn screening for cystic fibrosis (NBSCF) was initiated in March 2012. The impact on mutation distribution and clinical outcome for children diagnosed with cystic fibrosis (CF) has not yet been reported. The aim of this study was to compare the proportion of p.F508del homozygous pre- vs. post implementation of NBSCF, as well as sweat chloride (SC) levels, the prevalence of meconium ileus (MI) and use of pancreatic enzymes (PE). In addition, to compare chronic infections with Pseudomonas aeruginosa (PA) and Staphylococcus aureus (SA) at age five years.