Abstract

Objectives: Children and young people with CF taking elexacaftor/tezacaftor/ivacaftor (ETI), have shown increases in weight and BMI, however these markers do not distinguish between gain in fat mass (FM) or fat-free mass (FFM). FFM has a stronger association with FEV1 than BMI [ 1 Calella P et al. Nutrition. 2018; 55–56: 131-139 Crossref PubMed Scopus (40) Google Scholar ]. No studies have reported the impact of ETI on body composition (BC) in paediatric populations. We sought to assess anthropometry and BC in 6–11 year olds after starting ETI.

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