Abstract
A highly invasive fungus is associated with Epizootic Ulcerative Syndrome (EUS) in Indian fishes. The fungal invasion and associated pathology is not confined to the region of dermal ulcers. The fungus invades and proliferates in tissues away from the site of dermal ulcers and even penetrates across the vertebral septum to the contra-lateral side. The fungus readily invades the body cavity and produces mycotic granulomas in all the visceral organs. The invasive ability of the fungus is further demonstrated by its presence in the gizzard, spinal cord and intermuscular bones. The invasive nature of the fungus and associated tissue necrosis observed in a wide range of fresh and brackishwater fish hosts during natural epizootics present a plausible explanation for its high virulence and possible importance in defining the primary etiology of EUS.
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