Abstract
ABSTRACT Soft shell clams (Mya arenaria) were collected from tidal flats in southeastern New England, and their heamolymph analyzed for the presence of neoplastic cells. The prevalence of neoplasia varied from 10-90% with the highest prevalence found in New Bedford Harbor, a site containing high levels of pollutants, including PCBs, heavy metals and industrial wastes. Further analyses showed that quantifiable levels of Aroclors 1242 and 1254, congeners of PCB, could be detected in neoplastic cell extracts derived only from clams collected from New Bedford Harbor. These studies suggest an association between the high prevalence of disease and the location of soft shell clams at or near an industrially contaminated site.
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