Abstract

Epithelioid glioblastoma, a newly described rare variant of common tumor describing immunohistochemical expression pattern

Highlights

  • A 48-years old male presented to the Emergency Department of Neuro-surgery with the sudden onset of multiple episodes of vomiting, headache and weakness in the right half of body

  • The first case of Epithelioid glioblastoma (Ep-GBM) was reported by Kepes et al followed by few subsequent case reports

  • Ep-GBM possesses a poor outcome with survival less than the median survival time of 14.6 months in conventional GBM.[5]

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Summary

Introduction

Pathological findings: The tumor was comprised of large epithelioid cells arranged in sheets with perivascular clustering displaying eccentric nuclei with vesicular chromatin, prominent nucleolei and abundant amount of eosinophilic cytoplasm (Figure 2). Necrosis and atypical mitotic figures were noted.

Results
Conclusion
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